A bizarre method of potentially reversing brain ageing has been discovered in a study.

A bizarre method of potentially reversing brain ageing has been discovered in a study.

Many of us hope that defying the sands of time, often known as the brain ageing process, was as simple as counting 1, 2, 3. Unfortunately, we all succumb to the ageing process over time and frequently get slower as we get older.

Now, though, there may be a possibility of a solution. Scientists have discovered a strange approach to keep your brain from becoming old, according to a recent research published in the journal Nature Aging.

Your physical body will still age – there is no such thing as the Fountain of Youth – but you may still be able to act and feel young as you reach the end of your life.

faecal microbiota transplantation in Brain ageing

Scientists performed “faecal microbiota transplantation from either young (3–4 months) or elderly (19–20 months) donor mice into aged recipient mice (19–20 months)” in the study, which was carried out on mice. In human years, this would be the equivalent of transplanting faeces from an 18-year-old into a 70-year-old, according to the researchers.

The researchers discovered that transplanting juvenile faces into an older body helped to “encourage the establishment of gut microbiota mimicking the microbiome of younger mice.” The guts of the older mice began to operate more like those of the younger animals.

What's So Special About Einstein's Brain? | Charles River Laboratories.

The researchers looked examined the spatial memory of the elder mice to see if their assumption was correct. They did this by putting some mice with the faecal transplant and some mice without it into a water labyrinth where they had to construct a route to a dry platform.

The mice with the faecal transplant “discovered the platform with higher success than the mice without the transplant,” according to Inverse. This suggests that gut bacteria may have an influence on cognitive function.

Inverse provides some context for the findings by describing how the brain works in real life. “Your brain’s frontal cortex serves as a command centre for learning and memory processing.”

“The hippocampus is another part of the brain that helps us make and preserve memories. Both of these areas get smaller as you get older.”

Chemical messengers

“Aging is also associated with a decline in the synthesis of chemical messengers such as dopamine and serotonin in the brain. These are only a few of the reasons why older people have more problems remembering names, multitasking, and remembering where they left their keys.”

Of course, in the real world, we’re unlikely to see a young person’s faeces transplanted into an older person, but the study does emphasise the importance of the gut microbiota in connection to how our brain functions.

Fecal Matter Transfer has been used to successfully treat recurrent Clostridium difficile infection in people, according to the National Center for Biotechnology Information, and there are “preliminary indications to suggest that it may also carry therapeutic potential for other conditions such as inflammatory bowel disease, obesity, metabolic syndrome, and functional gastrointestinal disorders.”

This current rat study is the latest in a long line of research into the causes of ageing and potential ways to help slow down the entire process.

David Sinclair, an Australian biologist and professor of genetics, has dedicated his professional career to studying ageing and, with his team of researchers, has achieved significant advances in the field.

“The loss of epigenetic information is likely the core cause of ageing,” according to the Sinclair Lab at Harvard Medical School.

“If DNA is analogous to digital data on a compact disc, then ageing is caused by scratches.”

“We’re on the lookout for the polish.” David also believes that having only one meal per day might help slow down the ageing process.

During an episode of Joe Rogan’s podcast, The Joe Rogan Experience, David speculated that adjusting our meal frequency may help us live “healthier for longer.”

“We know that in controlled circumstances, if you do these things to animals [restrict eating], they live longer, a lot longer, maybe 20-30% longer because they’re healthier,” he added.

“They are immune to cancer, heart disease, and dementia.”

By “manipulating only one core pathway,” David Sinclair and his colleagues continue to study new drugs to help slow down the ageing process.

After all, the Fountain of Youth might not be such a far-fetched concept after all.

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